Setting Occupational Exposure Limits for Chemical Allergens—Understanding the Challenges
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چکیده
منابع مشابه
Setting Occupational Exposure Limits for Chemical Allergens--Understanding the Challenges.
Chemical allergens represent a significant health burden in the workplace. Exposures to such chemicals can cause the onset of a diverse group of adverse health effects triggered by immune-mediated responses. Common responses associated with workplace exposures to low molecular weight (LMW) chemical allergens range from allergic contact dermatitis to life-threatening cases of asthma. Establishin...
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Setting limits for safe exposure to toxic agents in the workplace is a complex process involving science, law, and policy. Development and use of occupational exposure limits (OELs) transcends national interests and international borders. Even though OELs have a lengthy history, and they form the cornerstone of most occupational risk assessment and risk management plans, their effectiveness in ...
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To set occupational exposure limits (OELs) for aerosol particles, dusts, or chemicals, one has to evaluate whether mechanistic considerations permit identification of a no observed effect level (NOEL). In the case of carcinogenic effects, this can be assumed if no genotoxicity is involved, and exposure is considered safe if it does not exceed the NOEL. If tumor induction is associated with geno...
متن کاملAn Overview of Setting Occupational Exposure Limits (OELs) for Pharmaceuticals
Introduction Occupational exposure limits (OELs) 1 for the protection of workers have been around at least since 1939 when the National (later changed to American) Conference of Governmental Industrial Hygienists (ACGIH) published its inaugural acceptable workplace exposure limits (now known as threshold limit values, or TLVs). In 1970, the U. S. Occupational Safety and Health Act incorporated ...
متن کاملAn overview of setting occupational exposure limits (OELs) for pharmaceuticals Setting appropriate occupational exposure limits is an integral component in assuring the health and safety of workers
INTRODUCTION Occupational exposure limits (OELs) for the protection of workers have been around at least since 1939 when the National (later changed to American) Conference of Governmental Industrial Hygienists (ACGIH) published its inaugural acceptable workplace exposure limits (now known as threshold limit values, or TLVs). In 1970, the U. S. Occupational Safety and Health Act incorporated by...
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ژورنال
عنوان ژورنال: Journal of Occupational and Environmental Hygiene
سال: 2015
ISSN: 1545-9624,1545-9632
DOI: 10.1080/15459624.2015.1072277